Optimizing Sample Handling for Urinary Proteomics

Handler Cloning for Optimizing Exception Handling

Handler cloning is a technique for optimizing exception handling. For a specific exception handler catching and rethrowing multiple classes of exceptions, it creates a clone of the original handler and registers the clone as a handler that catches only a single class or subset of the classes for the original handler. The rethrown exceptions from the clone are determined at the compile time.

Urinary proteomics for prediction of preeclampsia.

Preeclampsia is a major determinant of fetal and maternal morbidity and mortality. We used a proteomic strategy to identify urinary biomarkers that predict preeclampsia before the onset of disease. We prospectively collected urine samples from women throughout pregnancy. Samples from gestational weeks 12 to 16 (n=45), 20 (n=50), and 28 (n=18) from women who subsequently had preeclampsia develop...

urinary proteomics in nephrotic syndrome

nephrotic syndrome is the commonest glomerular disease. typical symptoms could be proteinuria, low serum albumin and oedema. the mechanism of proteinuria in nephrotic syndrome is a defective glomerular filtration barrier. renal biopsy is the gold standard for diagnosis of nephrotic syndrome currently which is invasive and based on histopathological features, therefore it seems to be necessary to...

Renal Transplantation and Urinary Proteomics

Data handling and processing in proteomics.

Martin Eisenacher, PhD Medizinisches ProteomCenter (MPC), RuhrUniversität Bochum, ZKF E.143, Universitätsstrasse 150, D-44801 Bochum, Germany Tel.: +49 234 322 9288 martin.eisenacher@ rub.de “...by providing all suitable proteomics data to public repositories and by subsequent reprocessing of these datasets, one also can obtain more information than from the single experiment, especially when c...